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Which of the following describes the correct administration of acetaminophen based on FDA recommendations?

  1. A maximum daily dose of 6 g

  2. A maximum daily dose of 4 g

  3. A maximum daily dose of 2 g

  4. No maximum dose required

The correct answer is: A maximum daily dose of 4 g

The correct administration of acetaminophen is based on FDA recommendations which currently state that the maximum daily dose should not exceed 4 grams in adults. This limit is established to prevent the risk of acute liver failure, which can result from excessive acetaminophen intake. This threshold is particularly important for those who consume alcohol regularly or have liver disease, as these factors may increase the risk of hepatotoxicity. Furthermore, acetaminophen is commonly found in many over-the-counter medications, including combination products, which can inadvertently lead patients to exceed the safe dosage. Thus, healthcare providers emphasize the significance of monitoring total daily intake. While the other options mention higher or lower maximum doses, they do not align with the current FDA guidelines, where staying within the 4 g limit is crucial for safety and efficacy.